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doi:10.1016/j.clinbiochem.2003.08.004

Despite initial pharmaceutical interest, AOD 9604 did not progress through the full clinical trial pathway required for regulatory approval, and it holds no Marketing Authorisation (MA) from the MHRA or EMA

Patients can also be at risk for low levels of B12 if they are taking certain medications such as antacids or antihistamines, which can block the absorption of B12

Reviewed against primary medical, regulatory, and trial sources for accuracy, sourcing, and patient-safety framing.

Precautions : Thiamine is generally safe if taken in the recommended dosages