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This article reports the effects of semaglutide 2.4 mg in individuals with biopsy-confirmed MASH and stage 2 or 3 fibrosis
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Multiply that across hundreds or thousands of employees, and the financial impact becomes staggering
Semaglutide can be used in patients with mild to moderate liver disease, but it should be used with caution
However, they should not be used with DPP-4 inhibitors (such as sitagliptin), and insulin or sulphonylurea doses may need adjustment to prevent hypoglycaemia
The copper-binding tripeptide has been shown to stimulate collagen synthesis in fibroblast cell cultures, promote decorin and glycosaminoglycan production, and modulate expression of metalloproteinases (MMPs) involved in extracellular matrix remodeling in vitro
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