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What it does is reduce local inflammation, support the maintenance of remaining tissue, and in some cases improve synovial health in a way that changes the pain experience meaningfully
In contrast, COX-1 is normally active in many tissues, where it has roles unrelated to inflammation (e.g., clotting function in blood platelets, mucus production from cells lining the GI tract) (Toussaint 2010
But almost no one has actually tested it in people
Every peptide vial is clearly labeled with the exact milligram amount, providing researchers with confidence in their measurements