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Side effects tend to mirror those of GLP-1 agonists: Nausea Diarrhea Decreased appetite Possible gallbladder effects (as with all rapid weight loss) Minimal risk of hypoglycemia when used without insulin Importantly, GIP on its own does not cause hypoglycemia , making it a relatively safe therapeutic target
J Clin Endocrinol Metab (1995) 80:9527
Administration is straightforward: subcutaneous injection with an insulin needle, once daily, self-administered at home
We dont know yet if immune responses to peptide sequences will mean its less effective over time or causes systemic symptoms
A recent surgery, trauma, or vaccine can trigger a gout attack or flare
The apical anion exchanger Slc26a6 promotes oxalate secretion by murine submandibular gland acinar cells
