Manson points out
The study, published in the Journal of Clinical Investigation Insight , showed that each time overweight mice stopped and restarted GLP-1s, they dropped less and less weight compared their original weight-loss
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However, these drugs have not been FDA-approved or evaluated for safety and effectiveness, including whether the ingredients are safe for human consumption
Therefore, treatment with GLP-1RAs shows favorable effects on anti-inflammation through the suppression of these proinflammatory cytokine and inflammatory signal pathways, as well as augmenting cholesterol efflux in the endothelium
Front Cell Infect Microbiol 7:160