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Cravings for high-calorie foods decrease noticeably within the first few weeks

12,15 Because the trials compared semaglutide with placebo, no head-to-head data were available to compare semaglutide with active treatments used in the management of overweight and obesity

Many describe the effect as similar to having an internal gastric band, since portions shrink and cravings, especially for calorie-dense foods, become less intense