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Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis
Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet
Increase this during hot weather, with exercise, or if you experience vomiting or diarrhea
Circana Mar 23 3 min read CHICAGO, March 23, 2026 The rise of GLP1 medication usage is emerging as a transformational force in the U.S
Patients should contact their GP or diabetes team if they experience: Severe, persistent abdominal pain (potential pancreatitis) Persistent vomiting leading to dehydration Signs of hypoglycaemia (if taking alongside insulin or sulphonylureas) Severe or persistent constipation or abdominal distension Right upper quadrant pain, fever or jaundice (potential gallbladder problems) Sudden visual changes (especially in those with diabetic retinopathy) Allergic reactions or injection site problems Weight loss typically becomes noticeable within the first few weeks to months, though the rate varies considerably between individuals