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The potential molecular mechanisms underlying these effects included disturbances in redox homeostasis (as evidence by the enhanced production of ROS and reactive nitrogen species), failure of enzymatic and nonenzymatic cytoprotective mechanisms involving the glutathione system as well as nuclear factor kappa B (NF-B) and fibroblast growth factor 2-mediated pathways, and impaired mitochondrial function

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A3 An amount of 50 mL of the biomass suspension (step A1) + 40 mL DMEM +10 mL sterile hydroalcoholic solution (90% H 2 0/10% EtOH) (total volume 100 mL, the reference preparation was without the matrix)

Role of oxidative stress and antioxidants in autism