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These are most common during dose escalation and often improve over time
2008;99:ES352
[5] It is important to note that whilst there appears to be an association, the precise causal relationship remains under investigation
however, gender- and age-specific responses, as well as concurrent medication use (eg, metformin), might influence outcomes
A conservative approach using 0.25 mg daily for the first two weeks allows assessment of individual response before considering increases
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