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This makes it a highly targeted tool for metabolic research
SARS-CoV-2 infection generates massive ROS production and the excessive oxidative damage is responsible for cytokine storm, undermined immunity, tissue damage and severe lung disease causing ARDS and death (Silvagno et al., 2020)
De Luca, C., Mikhalchik, E
In gastric cancer resistance models, upregulation of the cholesterol-HMGCR axis enhances lipid rafts and suppresses ferroptosis
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