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Whilst there is no established direct mechanism by which GLP-1 receptor agonists consistently cause joint pain, several indirect factors may explain why some patients experience musculoskeletal discomfort during treatment
Similarly, in another meta-analysis including 47 RCT and more than 23 thousand patients, patients receiving different GLP1RAs had a mean difference in weight of -5 kg relative to placebo [10]
Nevertheless, this does not make carnitine a performance enhancer or as was still believed in the early 1990s a fat burner that can then be marketed to people as a performance-boosting substance
No GLP-1 supplements use GRAS (Generally Recognized As Safe) ingredients and are regulated as dietary supplements, not FDA-approved drugs
doi: 10.1016/j.cmet.2014.10.006 44 JamesonEQuareshyMChenY
Then doctors started noticing the side-effect of weight lossand now here we are
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