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Similar results were found in several studies on the effects of metformin on the gut microbiota of patients with obesity or T2DM (de la Cuesta-Zuluaga et al., 2017
Negative or normal serum tests included coagulation panel Vitamin B3, Vitamin B12, methylmalonic acid, homocysteine, lead, mercury, thallium, arsenic, HIV, RPR hepatitis B/C serologies, Lyme, Bartonella, SPEP/UPEP, rheumatoid factor, anti-double-stranded DNA antibodies, anti-neutrophil cytoplasmic antibodies, anti-citric citrullinated peptide antibodies, anti-gliadin antibodies, anti-endomysial antibodies, cryoglobulins, anti-smith antibodies, anti-ribonucleoprotein antibodies, Sjogrens antibodies, IgG subclasses, IgE, complement C3 and C4 levels, angiotensin-converting enzyme, mitochondrial antibodies, GAD-65 autoantibodies, anti-GM1/2 antibodies, GQ1B antibodies, and Gd1a/b antibodies
Mike asks whether they conducted preclinical animal studies before human trials
Lutter M, Nestler EJ
Step 3: Lab Work (If Needed) If your intake reveals potential risks like prediabetes/diabetes, thyroid dysfunction, or liver or kidney disease, Found may order labs before approving treatment