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Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program

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doi: 10.1002/ijc.35286 203 YaoNLiWXuGDuanNYuGQuJ

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What the GLP-1 Conversation Is Getting Wrong Here is what gets left out: eating disorders are common in the very population most likely to be prescribed GLP-1 medications

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Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism

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