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In addition, PFOS can induce autophagy activation with increased Beclin and LC3BII expression through reactive oxygen species (ROS)-mediated extracellular signalregulated kinase (ERK) activation, which is followed by impeded autophagic flux, increased lysosomal membrane permeability (LMP), and, consequently, RTC apoptosis

Strenghts and limitations The principal strength of this study is the inclusion of patients from daily real-world clinical practice, with straightforward and simple inclusion criteria, which enhances the generalisability of the findings

INTRODUCTION Malaria remains a significant global health challenge, claiming the lives of over half a million children under the age of five annually [13]

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Semaglutide, sold as Ozempic, is prescribed to manage blood sugar levels in people with diabetes, reduce the risk of cardiovascular problems, and aid in weight loss

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