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Consequently, energy metabolism is affected, resulting in progressive motor dysfunction

Although regulation by redox environment occurs in the heterodimeric non-plant eukaryotic GCL, the plant GCL function as homodimeric enzymes with two intermolecular (not intramolecular) disulfide bonds (Hothorn et al., B

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Note that the only significant deviation of GSH in Panel B of Figure 2 occurs during days 10-14 when estradiol and S become very high, thus depressing the GSH concentration [Table 1]