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Isobaric 4OH-E2 and 2OH-E2, baseline separated at retention times of 8.76 min and 8.96 min, respectively, were detected using pairs of 571.2365.2 and 571.279.0
It inhibits the NF-kB p65 pathway by blocking phosphorylation at Ser536 and preventing nuclear translocation
p = 0.01 in patients with eGFR 60 ml/min/1.73 m 2 the changes of thoracic fluid index after liraglutide and placebo were similar (0.2 [95%CI ( 8.9)(9.2)] and 1.1 [95%CI ( 0.9)(3.0)], respectively) ( p = 0.50)
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