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Commenting on the divergence between their results and those of the original June 2025 study by Hathaway et al., the authors of the present study point to a few differences in methodology

In mice and humans taking metformin, a decrease in DPP4 levels is observed (Lenhard et al., 2004

Patients may experience gastrointestinal symptoms like diarrhea or upset stomach, but these quickly subside as your body adjusts to the medication

As more compounds reach market, identifying which works best for each individual becomes possible, potentially optimizing both efficacy and duration

But ultimately, you want to be thinner AND healthy

But their secondary use as a way for users to suppress diets and slim down sent sales through the roof