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In addition to its activity against hyperglycemia, DPP-4i has shown beneficial cardiovascular effects including cardioprotective action, endothelial protection, and an anti-hypertensive effect
Patients like the once-weekly subcutaneous injection programme because it makes it easier for them to stick to their drug plans than taking medications every day
7,8 In summary, the incretin mimetics exert actions to normalize blood glucose levels via multiple actions in the face of declining endogenous GLP-1 levels
Nature 479 , 232236 (2011)
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