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Exercise on its own sculpts the body and builds muscle
Explaining the approval process can help manage expectations
easily absorbed
Snyder reminds us that we need long-term data to understand the drug's safety and weight loss results
This sequential approach (start tirzepatide now, reassess in 2028) is the most practical strategy for many patients
Long-term follow-up in the DPPOS showed that adherent metformin users maintained roughly 6.2% weight loss below baseline after 15 years, demonstrating durable but modest results particularly in individuals with insulin resistance and higher BMI
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