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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency

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Heat, moisture, oxygen exposure, light, and repeated warming can still reduce quality over time

Because B12 is water soluble, your body does not store it, so it needs to be replenished on a consistent basis

The treatment plan usually starts with an intensive course before settling into a routine