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Pharmacological activation of hepatic TR potentiates the GLP-1 production Consistently, we found that pharmacological activation of hepatic TR by daily injection of MB07811, a liver-targeted TR-selective agonist, for five days could increase the plasma levels of GLP-1 and insulin, decrease the blood glucose levels, and as well as improve the oral glucose tolerance in MMI mice (Fig

Lisovsky M, Estrov Z, Zhang X, Consoli U, Sanchez-Williams G, Snell V, Munker R, Goodacre A, Savchenko V, Andreeff M

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