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[1] This formulation is designed for intranasal delivery in research environments, enabling controlled investigation of peptide absorption and receptor interaction across mucosal surfaces

However, translation of these findings to adult human obesity remains constrained by fundamental physiological differences, including limited brown adipose tissue mass and reduced thermogenic capacity

Mojsov's lab notes from 1983 includes her handwritten notations marking the key cleavage site in the preproglucagon sequence she considered critical to releasing the biologically active form of the peptide, namely GLP-1 (7-37)