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Key findings: 12 mg dose: Average weight loss of 24.2% of body weight (approximately 58 lbs for a 240 lb individual) 8 mg dose: Average weight loss of 22.8% 4 mg dose: Average weight loss of 17.0% Placebo: Average weight loss of 2.1% Over 90% of participants receiving the 8 mg or 12 mg dose lost at least 10% of body weight Over 75% of participants at the highest dose lost at least 20% of body weight Significant improvements in waist circumference, blood pressure, and lipid profiles were observed across dose groups Phase 2 Trial in Type 2 Diabetes A separate phase 2 trial evaluated retatrutide in adults with type 2 diabetes and obesity (Rosenstock et al., Lancet , 2023)

It's essential to discuss these options with a healthcare provider

Using scientifically-backed ingredients like berberine and chromium picolinate, this supplement helps regulate appetite, boost metabolism, and improve digestive function without synthetic hormones or pharmaceutical interventions

Long-term safety and efficacy data remain limited for both agents, as most clinical trials have been of relatively short duration

"FDA Approves New Medication for Chronic Weight Management." Accessed on November 7, 2023 at Lilly's Zepbound Official Website

GLP-1s are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)