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While FDA-approved peptide medications like semaglutide (Wegovy) and tirzepatide (Zepbound) have robust clinical evidence for weight loss of 15-20%+, many "research peptides" sold online (BPC-157, TB-500, AOD-9604) are unapproved drugs with unknown safety profiles, legal risks, and potential contamination

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A balanced diet with adequate protein, fiber, and healthy fats helps maintain satiety between meals