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In addition, in preclinical stages, a combination of GLP-1R agonism with N-methyl-D-aspartate (NMDA) receptor antagonism (GLP-1-MK-801) has been developed [115]

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In another study on German Holstein dairy cows, Scholzs group showed that supplementation with 2 g of LC/cow (contained in 10 g of a rumen-protected product) for three months improved metabolic health during the critical periods of transition and high lactation and showed a trend of improving milk production during the initial 2-months after calving