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After 6 h of treatment the GSH:GSSG ratio had decreased by 85% to 2.6:1 (Figure 5B)
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PET-CT, positron emission tomography/computed tomography
Ferroptosis is regulated by multiple cellular metabolic events, including redox homeostasis, iron metabolism, and amino acid metabolism [32, 33]
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DNA synthesis and cell metabolism Intracellular conversion of vitamin B 12 to two active coenzymes, in mitochondria and adenosylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine, respectively
