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Prescription semaglutide and other GLP-1 receptor agonists are regulated medicines with studied formulations, dosing, and monitoring

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Retatrutide is taken once weekly by subcutaneous injection, with doses escalated stepwise from a low starting dose

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These results highlight semaglutides early action on decreasing major cardiovascular events, with significant benefits already evident by the first 6 months, and for some, even earlier, even before any major weight loss and before most patients would have been titrated to their full target dose of 2.4 mg, said lead author Dr Jorge Plutzky, Director of Preventive Cardiology, Cardiovascular Medicine at Brigham and Womens Hospital, Boston, MA, USA and a member of SELECT Steering Committee

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