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10.1038/nm.3217 282 TsaiW

In cancer cells, increased lactate concentrations have been reported to suppress apoptosis through HIF-1-mediated upregulation of anti-apoptotic proteins, including BCL-2 and survivin, while concurrently promoting ferroptosis resistance via SCD1 upregulation (58,141)

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tumors, diabetic retinopathy) and long term oncologic outcomes

The cells were subsequently treated with DCFH-DA (10 M, Bio-lab) for 1 h in the dark, and washed three times with PBS