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Titration is patient-specific and requires ongoing provider oversight to assess response and tolerability
Wound healing: accelerated closure in rodent excision models Collagen synthesis: type I and III collagen upregulation in fibroblast cultures Hair biology: follicle enlargement observed in organ culture models Anti-fibrotic: decorin upregulation may limit scar tissue formation Antioxidant defense: SOD and catalase gene upregulation via copper-dependent pathways Evidence Base & Study Quality A critical distinction between these two peptides is the breadth of their evidence base
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The breadth of gene expression changes observed has been attributed to GHK-Cus role as a signaling molecule that interacts with multiple cellular systems simultaneously
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