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When the mini-gene was transiently transfected into differentiated mouse neuroblastoma N2a cells, E35a was completely skipped, similar to the splicing pattern of the endogenous Ank3 in non-neuronal cells and tissues

This pathway not only promotes proliferation but also alters mitochondrial bioenergetics in ways that support survival under therapeutic stress [70, 71]

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Some people might also notice mild diarrhea or a feeling of swelling in their body, but these are typically temporary

Transcriptome profiling of human post-mortem tissues (obtained from people aged between 16 and 102 years) found prominent and complex changes in gene expression in oligodendrocytes and astrocytes, whereas the neuronal transcriptome remained more or less undisturbed