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No serious adverse events have been systematically documented in human use to date, though the absence of systematic reporting infrastructure in the research peptide space means that adverse events are almost certainly underreported

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However, a postmortem study showed that GSH and GSH/GSSG were significantly decreased in the brains of ASD patients relative to controls 18 , suggesting that markers of glutathione metabolism may have parallel changes between central and peripheral in ASD

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Recent studies have shown that high doses of this substance led to a reduction in the acetylation of many lysine residues located on the N-terminal tail of histone H3 [131]