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As research continues and more long-term data becomes available, our understanding of the relative benefits of tirzepatide and semaglutide will likely evolve

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Subjects of the randomized controlled trial (RCT) are usually selected from relatively healthy individuals, patients with a history of MTC or pancreatitis may be excluded, RCT are not long enough to cause cancer AEs, and no RCT has tumor events as the primary outcome

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doi:10.3945/jn.114.202424 Shaikh K, Kinninger A, Cherukuri L, et al

Also, AG-270 showed a synergistic antiproliferative effect with the anti-mitotic drug taxane in vitro and in vivo