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*Correspondence: Hang Lin, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Tissue Engineering and Regenerative Medicine, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

It reduces methylationdriven consumption of NAM, increases substrate availability for NAD+ synthesis, and promotes NAD+ biosynthesis to elevate intracellular NAD+ levels

Patients with higher levels of fibrotic markers like S100A4 in blood or peritoneal fluid may be put on an anti-fibrotic regimen on priority

It is also known to fight disease, promote weight loss and fend off depression

A systematic review of NAC and antioxidant markers included 26 controlled studies