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Subunit structure of research subjects and rat glutathione S-transferases [PMID: 3902348] Laboratory literature summary: Subunit structure of research subjects and rat glutathione S-transferases
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With respect to dosage, the average reductions were: 2000 mcg: 71.5% (single data point) 1,000 mcg: 31.8% Although limited data are available for higher dosages, the findings support the efficacy of both oral and non-oral B12 formulations in modulating homocysteine levels
Second, GHK-Cu has a short half-life in tissue, less than one hour in serum according to pharmacokinetic studies
While these findings are promising, the complexity of human neurodegenerative diseases and the limitations of animal models necessitate cautious interpretation pending clinical validation