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Myocardial ischemia and reperfusion are accompanied by excessive production of reactive oxygen species (ROS), which contribute to ventricular dysfunction, arrhythmogenesis, and cardiomyocyte death
In estrogen receptor-positive breast cancer, XBP1s directly regulates the transcription of nuclear receptor coactivator 3 (NCOA3), linking UPR signaling to hormone receptor activity and therapy resistance
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Dioxins are a group of compounds related to dibenzofurans that are ubiquitous industrial and environmental pollutants
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