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It is FDA-approved specifically for HIV-associated lipodystrophy and is not approved for general weight loss

But an in-vitro permeability score is not the same as a measured oral bioavailability figure in an animal, and it is certainly not evidence of a human effect

summary Some animal studies suggest that a deficiency in vitamin B12 may increase body fat percentage and alter metabolism

The main symptoms are bloody diarrhea, stomach pain and frequently going to the toilet

Intramuscular therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms