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Due to the pleiotropic effects of GLP-1RAs, they become the basis of a new therapeutic strategy that affects both metabolic and neuropsychiatric aspects, which is fundamentally important for the treatment of comorbid diseases

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Region-specific neuronal toxicity has been linked to metabolic reprogramming in astrocytes, particularly in response to chronic stress and disease pathology 74

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As a copper-binding tripeptide, it acts as a signaling molecule, delivering copper ions to cells, which are essential for enzymatic activities and cellular functions

10.1111/jcmm.14622 92 WangY.LuX.LuJ.HernigouP.JinF