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Paradoxically, while tirzepatide decreases appetite, maintaining sufficient nutrition and fluids is critical for gut health
Thirdly, GLP-1 agonists slow gastric emptying, leading to a delayed absorption of nutrients and a prolonged feeling of fullness, which can contribute to reduced food intake and weight loss
Furthermore, regarding the mechanisms of GLP-1 secretion regulation in intestinal L-cells, including the potentiation mechanism of the main pathway, many unresolved aspects remain to be elucidated
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No prospective cohort studies
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