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Future research designs should go beyond simple body composition assessments, taking muscle strength, physical performance, and quality of life as core clinical endpoints to clarify the long-term effects of GLP-1RAs on different subgroups

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Further, the high-fat low-carbohydrate ketogenic diet (KD), which shifts metabolism towards fatty acid oxidation and away from glycolysis, also has antioxidant properties which may contribute to its clinical efficacy in Dravet Syndrome (Caraballo et al., 2005)

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