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75 Immune-excluded tumors are characterized by T cells confined to the stromal compartment, a state frequently driven by TGF-- or VEGF-dependent stromal programs
Optimum cellular metabolism
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Low Dose and Short Duration: When a potentially offending drug is necessary, use at the lowest effective dose for the shortest duration of therapy, if possible
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Shitara D, Nascimento MM, Puig S, Yamada S, Enokihara MM, Michalany N et al
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