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No mutagenic, carcinogenic, or teratogenic effects were observed in the preclinical datasets published by the Zagreb group
Increasing glutathione levels has been clinically shown to reduce free radical oxidative stress by strengthening the immunological response to inflammation
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Apart from differential compartmentation, one possibility is that this array of enzymes guarantees robust redox homeostasis, even at the expense of redundancy, consistent with loss-of-function studies for APX and PRX isoforms in the chloroplast (Awad et al
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