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Molar concentration conversion (for receptor pharmacology assays that require nanomolar concentrations): Molar concentration (M) = [mg/mL] / [MW in g/mol] 1,000,000 For cagrilintide (MW approximately 4,550 g/mol): - 1 mg/mL = approximately 220 M stock From a 220 M stock, you can dilute to nanomolar concentrations needed for receptor binding assays with simple serial dilution

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Native amylin readily forms amyloid fibrils protein aggregates that not only render the peptide non-functional but are also implicated in the pancreatic pathology of type 2 diabetes