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Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig

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The oral capsule format is designed for gastrointestinal pharmacology studies investigating local GI effects (gastric ulcer models, IBD models) and systemic bioavailability via the oral route

No obstante, la traduccin a humanos sigue siendo una hiptesis no verificada , ya que no se han completado ensayos clnicos de fase III

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Those looking for anti-aging benefits or general well-being may find glutathione to be a more versatile supplement