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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here

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References Amin, A

Ogru E, Wilson JC, Heffernan M, Jiang WJ, Chalmers DK, Libinaki R, Ng F

In lab tests, scientists have discovered that glutathione reduces oxidative stress

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