This is because tissues like the Achilles tendon or rotator cuff are highly avascularthey get very little blood flow
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In addition, curcumin intakes ranging from 0.45 to 3.6 g/day for up to four months did not increase leukocyte GST activity in humans (9)
It also activates the sympathetic nervous system, which directly stimulates immune cells
Cell 173 , 634648.e12 (2018)