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7 Tight junctions, which are functional barriers created by joining together endothelial cells, are made up of cytoplasmic accessory proteins (zona occludens-1, -2, and -3), which anchor the actin cytoskeleton to transmembrane proteins (claudins and occludin)

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Hydroxypropyl-alpha-cyclodextrins (CAS: 128446-33-3/99241-24-4) are commercially available, with an average molar substitution (MS) of 0.8 and a molar substitution range of 0.5-0.9