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Oral Semaglutide in Type 2 Diabetes: ClinicalMetabolic Outcomes and Quality of Life in Real-World Practice

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Measurable weight loss commonly starts within 4-6 weeks, with larger changes accumulating over 3-6 months

This creates a tension between therapeutic intensity and tolerability that is less pronounced in diabetes care

In addition, Fatty liver significantly elevates the risk of progressing from simple fibrosis to cirrhosis, and ultimately, liver cancer

In practical terms, as you lose weight: Your resting metabolic rate slightly decreases You burn fewer calories during movement Your body becomes more energy-efficient At this stage, small adjustments to calorie intake, protein distribution, or activity levels may help restart progress