The side effects of B12 shots vs IV infusions differ primarily in injection site reactions and systemic risks
Participants, with a mean age of 61 years, were randomly assigned to receive twice-weekly injections of either 50 mg of methylcobalamin or a placebo for 16 weeks (about four months)
PMID 16284435
This injection helps in improving nerve health, reducing numbness, and supporting overall body function
The duration of a B12 injections effects varies, but most people experience benefits for a few weeks to a few months
Factors such as initial B12 levels, underlying medical conditions, certain medications, advanced age, and injection frequency can affect the absorption and utilization of B12, possibly shortening the duration of action