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Metabolism directly informs the functional phenotypes of every cell present in the microenvironment (23)
2017 Apr;25(2):270-278
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These cells contribute to the permeability and integrity of the BBB through their intimate anatomical relationship (Liebner et al., Every constituent cell of the NVU contributes to the BBBs integrity, and any dysfunction might result in the barrier breakdown, with dramatic consequences such as neuroinflammation and neurodegeneration (Kempuraj et al., Inflammatory mediators are critical for BBB disruption
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