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Gastrointestinal changes can occur because KPV influences gut inflammation and BPC-157 affects gastric function
It has been demonstrated that the insulinotropic effect on -cells and glucagonostatic effect on -cells each contribute to about half of GLP-1s blood glucose-lowering activity (134)
Food reward functions as affected by obesity and bariatric surgery
PMC 3534976
The side effects are manageable with proper electrolyte and supplement protocols
On the other hand, while the triagonist, GLP1/GIP/Glucagon, was very effective in terms of body weight lowering, in keeping with previous references 42 , treatment of PWA mice led to a massive, likely detrimental weight loss, also at the expense of lean mass, that was not bound to clear amelioration of glucose intolerance in androgenized female mice
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